REYNOSA, TAMAULIPAS - Despite the "do not travel" warnings from the U.S. Department of State, thousands cross the border into the Mexican state of Tamaulipas every day.

Some of the people who live there know firsthand of the dangers; their pleas for help for the most part go unheard.

Just four days ago, Maria Isela Valdez knelt before Mexican President, Manuel Lopez Obrador, begging him to help her find her son.

He disappeared from Reynosa, the Mexican city across the border from Hidalgo, back in 2014.  

Valdez says her son left to work one day and never came back.

She is the founder of the group "10 de marzo" which in English means March 10, the date her son disappeared.

It's a group of mothers and family members who are all looking for their lost loved ones.

Valdez says, unfortunately, the numbers are spiraling out of control.

"There are 5,000 cases of missing people. Here in Reynosa it's prohibited for us to look for them. Here, we can't look for them, we can't ask questions - apparently nothing bad happens in Reynosa," she says.

She adds at least 80 families from the Rio Grande Valley are also missing loved ones and they're working with her organization to help find them.

For more information watch the video above.